hnn_core.calcium_model

hnn_core.calcium_model(params=None, add_drives_from_params=False, legacy_mode=False, mesh_shape=(10, 10))[source]

Instantiate the Jones 2009 model with improved calcium dynamics in L5 pyramidal neurons. For more details on changes to calcium dynamics see Kohl et al. Brain Topragr 2022 [1]

Returns:
netInstance of Network object

Network object used to store the Jones 2009 model with an improved calcium channel distribution.

See also

jones_2009_model

Notes

This model builds on the Jones 2009 model by using a more biologically accurate distribution of calcium channels on L5 pyramidal cells. Specifically, this model introduces a distance dependent maximum conductance (gbar) on calcium channels such that the gbar linearly decreases along the dendrites in the direction of the soma.

References

[1]

Kohl, Carmen, et al. “Neural Mechanisms Underlying Human Auditory Evoked Responses Revealed By Human Neocortical Neurosolver.” Brain Topography, 35, 19–35 (2022).